Advanced International Breast Cancer Course 2023
(AIBCC 2023)

Palazzo della Salute, Padova



Breast cancer research has been the frontrunner in many fields of cancer research: epidemiology, life-style and genetic risk factors, secondary prevention, conservative surgery, molecular classification, curative adjuvant therapies, neoadjuvant treatments, targeted agents, survival prolongation in advanced stages. Thanks to this knowledge, today many breast cancers can be prevented, most can be diagnosed at early stages and cured and the minority of patients at advanced stages can still enjoy a significant survival with a reasonable quality of life.

As a consequence of these major improvements, the bar of research and clinical excellence for breast cancer has raised even more.

New prognostic and predictive biomarkers are available, need to be validated and to be implemented in trial design and clinical practice. Risk-adapted surgery and radiation therapy allow for less and less invasive procedures. Multiple effective adjuvant therapies in the different molecular breast cancer subtypes, require a more precise definition of risk and predictivity of drug efficacy, to allow for a rational de-escalation or escalation of curative treatments. The impressive advances in the treatment of advanced breast cancers, envisage the possibility of cure with a multimodality approach for some patients and guarantee a prolonged survival for most of them with a rational sequencing of treatments.

The 19th AIBCC in Padova, will allow to sum up the most recent biological and clinical achievements and to allow an open and friendly discussion of clinical cases among key opinion leaders and participants.

Addressed to

  • Gynecologists and obstetrics

  • Medical oncologists

  • Pathologists

  • Radiologists

  • Radiation oncologists

  • Surgeons

  • Biologists

  • Pharmacists

  • Nurses

Scientific Program

Thursday, September 21st

10:00 Introduction to the Conference
Pierfranco Conte, Valentina Guarneri, Philip Poortmans, Aleix Prat

Chairpersons: Maria Vittoria Dieci, Hesham Ahmed Gaballah Elghazaly

10.30 Gene expression tools in early-stage HR+/HER2- breast cancer: when and which one?
Gaia Griguolo
11.00 Biological insights of the immune system in breast cancer
Maria Vittoria Dieci
11.30 DNA NGS-based biomarkers in advanced breast cancer: how, where and which ones?
Mafalda Oliveira
12.00 Tackling diversity in HER2-positive breast cancer: biological and clinical implications
Tomas Pascual
12.30 Discussion
13.00 Lunch
The changing relationship between locoregional recurrences and long-term outcomes

Chairpersons: Oreste Gentilini, Jacek Jassem, Eleftherios Mamounas

14.00 Mapping local and regional recurrences
Orit Kaidar-person
14.30 The surgical perspective
Eleftherios Mamounas
15.00 Deciphering the EBCTCG meta-analyses
Philip Poortmans
15.30 Discussion
Multidisciplinary Tumor Board 1 – Locoregional treatment
Panelists: Bettina Borisch, Oreste Gentilini, Jacek Jassem, Eleftherios Mamounas, Orit Kaidar-Person, Philip Poortmans, Hesham Ahmed Gaballah Elghazaly
16.00 Clinical case 1. Skin flap thickness for IBR
Rosa Di Micco
16.15 Clinical case 2. When to resect/irradiate after systemic therapy for a recurrence
Luca Visani
16.30 Clinical case 3: Local recurrence after DCIS
Eleonora Ferrara
16.45 General discussion and concluding comments
Jacek Jassem, Hesham Ahmed Gaballah Elghazaly
17.00 Adjourn
17.15 Ceremony for the presentation of the University of Padua Award for Advances in Breast Cancer 2023
17.30 Lecture of the Awardee
18.00 Adjourn

Friday, September 22nd


Chairpersons: Alessandra Gennari, Valentina Guarneri

9.00 New therapeutic strategies in very young women: lights and shadows
Angela Toss
9.20 Elderly patients: how old is too old in the contemporary scenario
Laura Biganzoli
9.40 Neoadjuvant approach: rethinking the paradigm?
Federica Miglietta
10.00 New ESMO Guidelines
Valentina Guarneri
10.20 Discussion
10.50 Coffee break
Multidisciplinary Tumor Board 2 – Early breast cancer
Panelists: Maria Vittoria Dieci, Alessandra Gennari, Valentina Guarneri, Eleftherios Mamounas, Sibylle Loibl, Philip Poortmans
11.15 Genomic test in premenopausal patients
Davide Massa
11.30 Adjuvant CDK 4/6 in patients with potential clinical indication but with low genomic risk
Michele Bottosso
11.45 HER2+ pt1cN0: adjuvant or neoadjuvant?
Ottavia Amato
12.00 General discussion and concluding comments
Alessandra Gennari
12.30 Lunch

Chairpersons: Giuseppe Curigliano, Pierfranco Conte

13.30 HR+ disease: is there any preferred treatment sequence at the time of endocrine-resistance?
Stephen Johnston
14.00 HER2+ disease: from guidelines to a personalized approach based on tumor and patient characteristics
Sandra Swain M
14.30 Triple negative disease: something more than label indications to dictate treatment sequence?
Hope Rugo
15.00 Discussion
Multidisciplinary Tumor Board 3 – Metastatic Breast Cancer
Panelists: Pierfranco Conte, Giuseppe Curigliano, Stephen Johnston, Hope Rugo
15.30 Clinical case 1. Visceral crisis
Grazia Maria Vernaci
15.45 Clinical case 2. Oligometastatic disease
Cristina Falci
16.00 Clinical case 3. Leptomeningeal metastases
Carlo Alberto Giorgi
16.15 General discussion and concluding comments
Hope Rugo
16.30 Take home messages and adjourn
Pierfranco Conte, Valentina Guarneri, Aleix Prat, Philip Poortmans

Award & Fellowship

University of Padova Award for advances in breast cancer 2023

The Scientific Committee will select young researchers (< 40 years from any country) who have published in an international peer-reviewed journal, as the principal author, a manuscript reporting important clinical or biological advances in breast cancer. The Scientific Commitee will select the final winner which will be invited to present his/her study during the annual Conference.


Some fellowship (for under 40) will be awarded including registration and 2 Hotel nights. Those interested should send a short CV and a motivation letter within September 7th to info.bologna@accmed.org The organizing secretariat will confirm the award of the fellowship within September 10th and proceed with the organization of logistics.

Under 40

Accademia will provide a limited amount of free registrations for Physicians, Biologists, Pharmacists and Nurses “Under 40”. Those interested should send email within September 7th to info.bologna@accmed.org. The organizing secretariat will confirm the registration by email.


Honorary President

Gabriel N. Hortobagyi
Gabriel N. HortobagyiHouston (US)
Department of Breast Medical Oncology
The University of Texas – MD Anderson Cancer Center


Pierfranco Conte
Pierfranco ConteVenezia (IT)
Coordinator Molecular Tumor Board, Rete Oncologica Veneta, Padova (IT)
Scientific Director S. Camillo Hospital, IRCCS, Venezia (IT)
Valentina Guarneri
Valentina GuarneriPadova (IT)
Division of Medical Oncology 2
Istituto Oncologico Veneto IRCCS
Department of Surgery, Oncology and Gastroenterology
Philip Poortmans
Philip PoortmansWilrijk-Antwerp (BE)
Former president of ESTRO and of ECCO
Department of Radiation Oncology
Iridium Netwerk
University of Antwerp (BE)
Aleix Prat
Aleix PratBarcellona (ES)
Director Clínic’s Institute of Hematological and Oncological Diseases (ICMHO)
University Barcellona (ES)

Scientific Commitee

Bettina Borisch
Geneve (CH)

Maria Vittoria Dieci
Padova (IT)

Hesham Ahmed Gaballah Elghazaly
Cairo (EG)

Jacek Jassem
Gdansk (PL)

Stephen Johnston
London (UK)

Sibylle Loibl
Frankfurt (DE)

Eleftherios Mamounas
Orlando (US)

Miguel Martin
Madrid (ES)

Fedro Alessandro Peccatori
Milano (IT)

Sandra M. Swain
Washington (US)


Ottavia Amato
Padova (IT)

Laura Biganzoli
Prato (IT)

Michele Bottosso
Padova (IT)

Giuseppe Curigliano
Milano (IT)

Rosa Di Micco
Milano (IT)

Cristina Falci
Padova (IT)

Eleonora Ferrara
Novara (IT)

Alessandra Gennari

Oreste Davide Gentilini
Milano (IT)

Carlo Alberto Giorgi
Padova (IT)

Gaia Griguolo
Padova (IT)

Orit Kaidar-Person
Ramat Gan (IL)

Davide Massa
Padova (IT)

Federica Miglietta
Padova (IT)

Mafalda Oliveira
Barcellona (ES)

Tomàs Pascual
Barcellona (ES)

Hope Rugo
San Francisco (US)

Angela Toss
Modena (IT)

Hope Rugo
San Francisco (US)

Grazia Vernaci
Padova (IT)

Luca Visani
Firenze (IT)

Download all the slides of AIBCC 2022.

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