18th MEET THE PROFESSOR

Advanced International Breast Cancer Course 2022
(AIBCC 2022)

Presentation

Aims

Breast cancer research has been the frontrunner in many fields of cancer research: epidemiology, life-style and genetic risk factors, secondary prevention, conservative surgery, molecular classification, curative adjuvant therapies, neoadjuvant treatments, targeted agents, survival prolongation in advanced stages. Thanks to this knowledge, today many breast cancers can be prevented, most can be diagnosed at early stages and cured and the minority of patients at advanced stages can still enjoy a significant survival with a reasonable quality of life.
As a consequence of these major improvements, the bar of research and clinical excellence for breast cancer has raised even more.
New prognostic and predictive biomarkers are available, need to be validated and to be implemented in trial design and clinical practice. Risk-adapted surgery and radiation therapy allow for less and less invasive procedures. Multiple effective adjuvant therapies in the different molecular breast cancer subtypes, require a more precise definition of risk and predictivity of drug efficacy, tio allow for a rational de-escalation or escalation of curative treatments. The impressive advances in the treatment of advanced breast cancers, envisage the possibility of cure with a multimodality approach for some patients and guarantee a prolonged survival for most of them with a rational sequencing of treatments.
The 18th AIBCC in Padova, will allow to sum up the most recent biological and clinical achievements and to allow an open and friendly discussion of clinical cases among key opinion leaders and participants.

Addressed to

  • Gynecologists and obstetrics

  • Medical oncologists

  • Pathologists

  • Radiologists

  • Radiation oncologists

  • Surgeons

  • Biologists

  • Pharmacists

  • Nurses

Scientific Program

Thursday, November 3rd

10:00 Introduction to the Conference
Pierfranco Conte, Valentina Guarneri, Philip Poortmans, Aleix Prat
SESSION I – EVOLVING KNOWLEDGE OF BREAST CANCER BIOLOGY: IMPLICATIONS FOR STAGING, PROGNOSIS AND PREDICTION

Chairpersons: Hesham Ahmed Gaballah Elghazaly, Aleix Prat

10:30 Biological heterogeneity and clinical outcomes in HR+/HER2-negative disease
Maria Vittoria Dieci
11:00 PDL1, TMB, TROP2, immune infiltration and genomic classifiers in TNBC
Giampaolo Bianchini
11:30 Is HER2-low breast cancer a real entity? Scoring issues and biological heterogeneity
Giuseppe Viale
12:00 HER2+ early breast cancer: potential role of genomic classifiers
Aleix Prat
12:30 Q&A
13:00 Lunch

SESSION II – CHANGING PARADIGMS FOR LOCOREGIONAL TREATMENTS
Mastectomy, breast reconstruction and radiation Therapy

Chairpersons: Jaceck Jassem, Philip Poortmans

14:00 When is breast-conserving therapy really not avoidable
Oreste Gentilini
14:30 Breast reconstruction: when and how?
Vincenzo Vindigni
15:00 Radiation therapy after breast reconstruction
Orit Kaidar-Person
15:30 Q&A
  Multidisciplinary Tumor Board 1 – Locoregional treatment
Panelists: Bettina Borisch, Oreste Gentilini, Jacek Jassem, Eleftherios Mamounas, Orit Kaidar-Person, Philip Poortmans, Fedro Peccatori
16:00 Clinical case 1. Second breast conserving therapy
Tania Saibene
16:15 Clinical case 2. Patient with lymph node seen on planning CT-scan: what now? (RT)
Silvia Michieletto
16:30 Clinical case 3: BOOP: after or due to radiation therapy
Luca Visani
16:45 Concluding comments
Eleftherios Mamounas, Fedro Peccatori
17:00 Adjourn
17:45 Ceremony for the presentation of the University of Padua Award for Advances in Breast Cancer 2022
18:00 Lecture of the Awardee
18:30 Cocktail
19:00 Adjourn

The Ceremony and the cocktail will take place in
Palazzo Bo, Via VIII Febbraio 2, Padua

Friday, November 4th

SESSION III – EARLY BREAST CANCER. FINE TUNING FROM DE-ESCALATION TO ESCALATION

Chairpersons: Pierfranco Conte, Miguel Martin.

09:00 Tailoring neoadjuvant/adjuvant treatment for triple negative breast cancer
Sibylle Loibl
09:30 Risk adapted treatment of early HR+/HER2- breast cancer: from modulation of endocrine treatment to novel agents
Stephen Johnston
10:00 Is there a role for anthracyclines in contemporary treatment of early breast cancer?
Valentina Guarneri
10:30 Q&A
11:00 Coffee Break
  Multidisciplinary Tumor Board 2 – Early breast cancer
Panelists: Bettina Borisch, Pierfranco Conte, Valentina Guarneri, Jacek Jassem, Stephen Johnston, Sibylle Loibl, Miguel Martin, Fedro Peccatori
11:30 Clinical case 1. Node positive, premenopausal patient: role of genomic classifiers
Cristina Falci
11:45 Clinical case 2. HR+HER2+ patient with residual disease after neoadjuvant therapy
Federica Miglietta
12:00 Clinical case 3. Adjuvant treatment in rare histologies
Grazia Vernaci
12:15 Concluding comments
Jaceck Jassem, Miguel Martin
12:30 Lunch
SESSION IV – METASTATIC BREAST CANCER: NEW OPTIONS, NEW ALGORITHMS

Chairpersons: Alessandra Gennari, Bettina Borisch.

13:30 HER2+ advanced breast cancer: new treatment algorithms
Sandra Swain
14:00 TN advanced breast cancer: biology-driven treatment algorithms
Hope Rugo
14:30 HR+ advanced breast cancer: what after CDK4/6?
Giuseppe Curigliano
15:00 Q&A
  Multidisciplinary Tumor Board 3 – Metastatic Breast Cancer
Panelists: Bettina Borisch, Pierfranco Conte, Giuseppe Curigliano, Hesham Ahmed Gaballah Elghazaly, Hope Rugo, Sandra Swain
15:30 Clinical case 1. Brain metastases
Gaia Griguolo
15:45 Clinical case 2. Possibility of discontinuing treatment in very long term responders
Carlo Alberto Giorgi
16:00 Clinical case 3. Locoregional treatment for oligometastatic disease or role of NGS in ABC
Michele Bottosso
16:15 Concluding comments
Pierfranco Conte, Hesham Ahmed Gaballah Elghazaly
16:30 Take home messages and adjourn

In-Class Course

PADUA, November 3rd (10:15 – 18:30) | November 4th (09:00 – 16:30)

ENROLL

Follow the link below to enroll in the in-class course. Please note that the available places are limited.

The official language of the course is English. No simultaneous translation will be provided.

You can find further details on the security measures for the residential event here: https://fad.accmed.org/sicurezza.

Registration

The standard registration fee is € 250,00. The reduced registration fee for graduate students and nurses is € 150,00.
Online registration is available at this link until 20th October 2022.

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Meeting Venue

Auditorium – San Gaetano Altinate Cultural Center
Via Altinate, 71, Padua

The Center is located in the ZTL area. We recommend the parking in Piazza Insurrezione in the historic center of Padua (the area is accessible and there are no electronic gates).

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Online Course

Online, November 3rd (10:15 – 18:30) | November 4th (09:00 – 16:30)

ENROLL

The Online Course will allow participants to attend to AIBCC 2022 from anywhere in the world. Follow the link below to enroll in the online course.

The official language of the course is English. No simultaneous translation will be provided.

To follow the online course, participants will need a good quality internet connection and a device (PC, Smartphone, Tablet) capable of running a recent Internet browser (e.g. any updated version of Chrome or Firefox).

Registration

The standard registration fee is € 180,00. The reduced registration fee for graduate students and nurses is € 100,00.

CME (In-Class & Online)

Based on the applicable regulation, Accademia Nazionale di Medicina (CME provider n. 31) will assign to the activity (ECM 31-355554): 8,4 CME points.

Training objective: professional and technical content (knowledge and skills) specific to each profession, specialization and highly specialized activity. Rare disease.

The credit certification for the course is subject to the fulfillment of all following conditions:

  • Professions/specializations should correspond to those accredited for CME
  • Attendance no lower than 90% of the meeting duration
  • Completion of the meeting evaluation online form
  • Completion of the final test (at least 75% of correct answers). 1 attempt admitted.
  • Ownership of an Italian Fiscal Code (Codice Fiscale).

The test and the meeting evaluation form must be completed within 3 days from the end of the event.

Educational material

The event educational material can be downloaded starting November 20th on askit.accmed.org

Award & Fellowship

University of Padua Award for advances in breast cancer 2022

The Scientific Committee will select young researchers (< 40 years from any country) who have published in an international peer-reviewed journal, as the principal author, a manuscript reporting important clinical or biological advances in breast cancer. The Scientific Commitee will select the final winner which will be invited to present his/her study during the annual Conference.

Fellowship

Some fellowship (for under 40) will be awarded including registration and 2 Hotel nights. Those interested should send a short CV and a motivation letter within October 10th to info.bologna@accmed.org The organizing secretariat will confirm the award of the fellowship within October 20th and proceed with the organization of logistics.

Under 40

Accademia will provide a limited amount of free registrations for Physicians, Biologists, Pharmacists and Nurses “Under 40”. Those interested should send email within October 10th to info.bologna@accmed.org. The organizing secretariat will confirm the registration by email.

Faculty

Honorary President

Gabriel N. Hortobagyi
Gabriel N. HortobagyiHouston (USA)
Department of Breast Medical Oncology
The University of Texas – MD Anderson Cancer Center

Directors

Pierfranco Conte
Pierfranco ContePadova (I)
Division of Medical Oncology 2
Istituto Oncologico Veneto IRCCS
Department of Surgery, Oncology and Gastroenterology
Valentina Guarneri
Valentina GuarneriPadova (I)
Division of Medical Oncology 2
Istituto Oncologico Veneto IRCCS
Department of Surgery, Oncology and Gastroenterology
Philip Poortmans
Philip PoortmansWilrijk-Antwerp (B)
Former president of ESTRO and of ECCO
Department of Radiation Oncology
Iridium Netwerk
University of Antwerp
Aleix Prat
Aleix PratBarcellona (E)
Medical Oncology Department
Hospital Clinic

Scientific Commitee

Bettina Borisch
Geneve (CH)

Maria Vittoria Dieci
Padova (I)

Hesham Ahmed Gaballah Elghazaly
Cairo (EG)

Jacek Jassem
Gdansk (PL)

Stephen Johnston
London (UK)

Sibylle Loibl
Frankfurt (D)

Eleuterios Mamounas
Orlando (USA)

Miguel Martin
Madrid (E)

Fedro Alessandro Peccatori
Milano (I)

Sandra M. Swain
Washington (USA)

Speakers

Giampaolo Bianchini
Milano (I)

Michele Bottosso
Padova (I)

Giuseppe Curigliano
Milano (I)

Maria Vittoria Dieci
Padova (I)

Cristina Falci
Padova (I)

Alessandra Gennari
Novara(I)

Valentina Guarneri
Padova (I)

Oreste Davide Gentilini
Milano (I)

Carlo Alberto Giorgi
Padova (I)

Gaia Griguolo
Padova (I)

Orit Kaidar-Person
Ramat Gan (IL)

Stephen Johnston
London (UK)

Sibylle Loibl
Frankfurt (D)

Silvia Michieletto
Padova (I)

Federica Miglietta
Padova (I)

Aleix Prat
Barcellona (E)

Hope Rugo
San Francisco (USA)

Tania Saibene
Padova (I)

Sandra Swain M.
Washington (USA)

Grazia Vernaci
Padova (I)

Giuseppe Viale
Milano (I)

Vincenzo Vindigni
Padova (I)

Luca Visani
Firenze (I)

Download all the slides of AIBCC 2021.

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